[{"@context":"https:\/\/schema.org\/","@type":"Article","@id":"https:\/\/www.lmat.cz\/zmena-dna\/#Article","mainEntityOfPage":"https:\/\/www.lmat.cz\/zmena-dna\/","headline":"Zm\u011bna DNA","name":"Zm\u011bna DNA","description":"Nen\u00ed to tak dlouho co do\u0161lo k velk\u00e9mu odhalen\u00ed prvn\u00edho pokusu o zm\u011bn\u011bn\u00ed lidsk\u00e9ho genomu a \u00faprav\u011b jejich polynukleotidov\u00e9ho \u0159et\u011bzce tvo\u0159\u00edc\u00ed dvou\u0161roubovice DNA. Bylo tomu minul\u00fd rok, co \u010d\u00ednsk\u00fd biofyzik Che \u0164ien-kchuej ve\u0159ejn\u011b vystoupil a odhalil sv\u00e9 pro n\u011bkoho pokrokov\u00e9 a odv\u00e1\u017en\u011b pro jin\u00e9 d\u011bsiv\u00e9, proti p\u0159\u00edrod\u011b, zvr\u00e1cen\u00e9 pokusy. Tento \u010d\u00ednsk\u00fd pr\u016fkopn\u00edk geneticky pozm\u011bnil dv\u011bma […]","datePublished":"2019-03-01","dateModified":"2019-03-01","author":{"@type":"Person","@id":"https:\/\/www.lmat.cz\/author\/#Person","name":"","url":"https:\/\/www.lmat.cz\/author\/","identifier":1,"image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/1e120f96477763896a9e7ab3663c076bf8b67ca32fa1a5943b70761da502a7a7?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/1e120f96477763896a9e7ab3663c076bf8b67ca32fa1a5943b70761da502a7a7?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"lmat.cz","logo":{"@type":"ImageObject","@id":"\/logo.png","url":"\/logo.png","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/www.lmat.cz\/wp-content\/uploads\/img_a341275_w2634_t1553972933.jpg","url":"https:\/\/www.lmat.cz\/wp-content\/uploads\/img_a341275_w2634_t1553972933.jpg","height":0,"width":0},"url":"https:\/\/www.lmat.cz\/zmena-dna\/","wordCount":423,"articleBody":"Nen\u00ed to tak dlouho co do\u0161lo k velk\u00e9mu odhalen\u00ed prvn\u00edho pokusu o zm\u011bn\u011bn\u00ed lidsk\u00e9ho genomu a \u00faprav\u011b jejich polynukleotidov\u00e9ho \u0159et\u011bzce tvo\u0159\u00edc\u00ed dvou\u0161roubovice DNA. Bylo tomu minul\u00fd rok, co \u010d\u00ednsk\u00fd biofyzik Che \u0164ien-kchuej ve\u0159ejn\u011b vystoupil a odhalil sv\u00e9 pro n\u011bkoho pokrokov\u00e9 a odv\u00e1\u017en\u011b pro jin\u00e9 d\u011bsiv\u00e9, proti p\u0159\u00edrod\u011b, zvr\u00e1cen\u00e9 pokusy. Tento \u010d\u00ednsk\u00fd pr\u016fkopn\u00edk geneticky pozm\u011bnil dv\u011bma hol\u010di\u010dk\u00e1m dvoj\u010d\u00e1tk\u016fm jejich, jednodu\u0161e \u0159e\u010deno, DNA. Che na sv\u00e9 konferenci, kde do\u0161lo k tomuto velk\u00e9mu a dech berouc\u00edmu odhalen\u00ed podrobn\u011b vysv\u011btlil, jak, a p\u0159edev\u0161\u00edm pro\u010d, vyu\u017eil u\u017e n\u011bkolik let, dobr\u011b zn\u00e1mou, metodu CRISR. Tato metoda je pom\u011brn\u011b dob\u0159e zn\u00e1ma jako dom\u00e1c\u00ed tov\u00e1rna na \u00fapravu genetick\u00e9ho k\u00f3du, kter\u00fd je i pom\u011brn\u011b dob\u0159e cenov\u011b p\u0159\u00edstupn\u00fd. Ale k \u010demu p\u0159esn\u011b do\u0161lo \u00fapravou genetick\u00e9ho k\u00f3du mal\u00fdch dvoj\u010dat? Che vysv\u011btlil, \u017ee za pomoci zm\u00edn\u011bn\u00e9 metody, deaktivoval receptor CCR5, kter\u00fd je zodpov\u011bdn\u00fd za jednu z nejob\u00e1van\u011bj\u0161\u00edch chorob posledn\u00edch pades\u00e1ti let. Sourozenci, kte\u0159\u00ed byli sv\u011b\u0159en\u00ed do p\u00e9\u010de \u010dasto p\u0159ezd\u00edvan\u00e9mu \u201e\u010d\u00ednsk\u00e9mu doktoru Frankensteinovi\u201c by m\u011bli b\u00fdt, d\u00edky sv\u00e9 malink\u00e9 zm\u011bn\u011b, imunn\u00ed oproti viru HIV, a tud\u00ed\u017e i choroby AIDS, s kterou si st\u00e1le v dne\u0161n\u00ed dob\u011b nev\u00edme, tak \u00fapln\u011b rady. To je by p\u0159ece m\u011blo b\u00fdt skv\u011bl\u00e9, \u017ee se zde na\u0161el zp\u016fsob, jak ochr\u00e1nit sv\u00e9 potomky p\u0159ed touto ni\u010divou chorobou. Ale s touto zm\u011bnou p\u0159i\u0161li i jin\u00e9 vedlej\u0161\u00ed \u00fa\u010dinky. Mal\u00e9 d\u011bti by m\u011bli m\u00edt i vy\u0161\u0161\u00ed inteligenci a zv\u00fd\u0161en\u00e9 kognitivn\u00ed schopnosti. To v\u0161echno vyvol\u00e1v\u00e1 etick\u00e9 ot\u00e1zky, zda byl tento z\u00e1krok, eticky spr\u00e1vn\u00fd, \u010di ne. Ale v jak\u00e9m sv\u011bt\u011b se to ocitneme, bude-li p\u016flka obyvatel planety \u201evylep\u0161en\u00e1\u201c geneticky modifikovan\u00e1, tud\u00ed\u017e i chyt\u0159ej\u0161\u00ed a siln\u011bj\u0161\u00ed, a druh\u00e1 polovina nikoli. Dojde snad rozd\u011blen\u00ed obyvatelstva na dv\u011b kasty? Na kastu nadlid\u00ed, kte\u0159\u00ed budou m\u00edt v\u00edce privilegii a v\u011bt\u0161\u00ed \u0161ance v cel\u00e9m sv\u00e9m \u017eivot\u011b a na druhou polovinu, oby\u010dejn\u00fdch lid\u00ed, kte\u0159\u00ed budou pova\u017eov\u00e1ni za pod\u0159adn\u00e9, a nikdy nedostanou svoji p\u0159\u00edle\u017eitost? Budoucnost n\u00e1m le\u017e\u00ed na dlani a je jenom na n\u00e1s, jak se rozhodneme.                                                                                                                                                                                                                                                                                                                                                                                         4.6\/5 - (9 votes)        "},{"@context":"https:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Zm\u011bna DNA","item":"https:\/\/www.lmat.cz\/zmena-dna\/#breadcrumbitem"}]}]